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- 2 Laufend
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TARGET MPN: Targeting Kindlin-3-mediated integrin activation and signaling to eradicate persistent MPN clones
Krenn, P. (Projektleitung) & Lankes, D. (Projektmitarbeiter/in)
1/07/24 → 30/06/28
Projekt: Forschung
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Novel Inhibitors: Novel Inhibitors targeting oncogenic Hedgehog/GLI signaling
Aberger, F. (Projektleitung), Krenn, P. (Projektmitarbeiter/in) & Aichberger, S. K. (Projektmitarbeiter/in)
1/09/23 → 31/12/24
Projekt: Forschung
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ADP-heptose attenuates Helicobacter pylori-induced dendritic cell activation
Neuper, T., Frauenlob, T., Dang, H.-H., Krenn, P. W., Posselt, G., Regl, C., Fortelny, N., Schäpertöns, V., Unger, M. S., Üblagger, G., Neureiter, D., Mühlbacher, I., Weitzendorfer, M., Singhartinger, F., Emmanuel, K., Huber, C. G., Wessler, S., Aberger, F. & Horejs-Hoeck, J., 17 Sept. 2024, in: Gut Microbes. 16, 1, S. 2402543Publikation: Beitrag in Fachzeitschrift › Artikel › Peer-reviewed
Open Access -
Targeting NLRP3 inhibits AML progression by inducing PERK/eIF2-mediated apoptosis
Luciano, M., Sieberer, H., Krenn, P. W., Dang, H.-H., Vetter, J., Neuper, T., Amend, D., Blöchl, C., Weichenberger, C. X., Eglseer, A., Unger, M. S., Andosch, A., Steiner, P., Neureiter, D., Bauer, R., Hummer, L., Tesanovic, S., Binder, S., Elmer, D. P. & Strandt, H. &10 mehr, , 2 Sept. 2024, in: Cell Communication and Signaling. 22, 1, S. 424 424.Publikation: Beitrag in Fachzeitschrift › Artikel › Peer-reviewed
Open Access -
Hedgehog-Hippo pathway interactions promote T cell exclusion from the tumor microenvironment in basal cell carcinoma
Stockmaier, G., Varkhande, S., Krenn, P., Dang, H.-H., Sharma, A., Elmer, D. P., Steiner, M., Zaborsky, N., Neureiter, D., Greil, R., Horejs-Hoeck, J., Fortelny, N. & Aberger, F., 2024, bioRxiv.Publikation: Working paper/Preprint › Preprint
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Targeting cancer hallmark vulnerabilities in hematologic malignancies by interfering with Hedgehog/GLI signaling
Krenn, P. W. & Aberger, F., 7 Dez. 2023, in: BLOOD. 142, 23, S. 1945-1959 15 S.Publikation: Beitrag in Fachzeitschrift › Review article › Peer-reviewed
Open Access -
The Class IIA Histone Deacetylase (HDAC) Inhibitor TMP269 Downregulates Ribosomal Proteins and Has Anti-Proliferative and Pro-Apoptotic Effects on AML Cells
Urwanisch, L., Unger, M. S., Sieberer, H., Dang, H.-H., Neuper, T., Regl, C., Vetter, J., Schaller, S., Winkler, S. M., Kerschbamer, E., Weichenberger, C. X., Krenn, P. W., Luciano, M., Pleyer, L., Greil, R., Huber, C. G., Aberger, F. & Horejs-Hoeck, J., 7 Feb. 2023, in: Cancers. 15, 4, 1039.Publikation: Beitrag in Fachzeitschrift › Artikel › Peer-reviewed
Open Access
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GLI-YAP interactions in basal cell carcinoma promote immune evasion by regulating the spatial distribution of immune responses.
Krenn, P. (Redner/in), Stockmaier, G. (Redner/in), Varkhande, S. (Redner/in), Dang, H.-H. (Redner/in), Sharma, A. (Redner/in), Elmer, D. P. (Redner/in), Steiner, M. (Redner/in), Zaborsky, N. (Redner/in), Neureiter, D. (Redner/in), Greil, R. (Redner/in), Horejs-Höck, J. (Redner/in), Fortelny, N. (Redner/in), Gratz, I. K. (Redner/in) & Aberger, F. (Redner/in)
12 Dez. 2024Aktivität: Gastvortrag oder Vortrag › Poster-Präsentation › science to science / art to art
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Characterizing and disrupting leukemic stem cell interactions with their supportive microenvironment
Krenn, P. (Redner/in)
29 Nov. 2024Aktivität: Gastvortrag oder Vortrag › Vortrag › science to science / art to art
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ADP-heptose attenuates H. pylori-induced DC activation
Neuper, T. (Redner/in), Frauenlob, T. (Redner/in), Dang, H.-H. (Redner/in), Krenn, P. (Redner/in), Posselt, G. B. (Redner/in), Regl, C. (Redner/in), Fortelny, N. (Redner/in), Schäpertöns, V. (Redner/in), Unger, M. S. (Redner/in), Üblagger, G. L. (Redner/in), Neureiter, D. (Redner/in), Mühlbacher, I. (Redner/in), Weitzendorfer, M. (Redner/in), Singhartinger, F. (Redner/in), Emmanuel, K. (Redner/in), Huber, C. (Redner/in), Weßler, S. (Redner/in), Aberger, F. (Redner/in) & Horejs-Höck, J. (Redner/in)
3 Juli 2024 → 6 Juli 2024Aktivität: Gastvortrag oder Vortrag › Poster-Präsentation › science to science / art to art
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Effects of ADP-heptose on human primary dendritic cells
Neuper, T. (Redner/in), Frauenlob, T. (Redner/in), Dang, H.-H. (Redner/in), Posselt, G. B. (Redner/in), Regl, C. (Redner/in), Krenn, P. (Redner/in), Unger, M. S. (Redner/in), Huber, C. (Redner/in), Aberger, F. (Redner/in), Fortelny, N. (Redner/in), Weßler, S. (Redner/in) & Horejs-Höck, J. (Redner/in)
2 Dez. 2023 → 5 Dez. 2023Aktivität: Gastvortrag oder Vortrag › Vortrag › science to science / art to art
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Deciphering the regulation and function of integrin activators Kindlin-3 and Talin-1 in leukemic (stem) cells using in vitro and in vivo models
Lankes, D. (Redner/in), Doma, E. (Redner/in), Mayer, L. (Redner/in), Sexl, V. (Redner/in), Koschmieder, S. (Redner/in), Aberger, F. (Redner/in) & Krenn, P. (Redner/in)
20 Sept. 2023Aktivität: Gastvortrag oder Vortrag › Poster-Präsentation › science to science / art to art