Quantitative detection of bacterial ENDOtoxin by novel NANOtechnological approaches



The scientific and technological goals of ENDONANO include: 1. Investigating the capacity of endotoxin to specifically inducing inflammatory reactions in human primary blood cells; 2. Developing new methods based on endotoxin capture by metal nanoparticles in complex matrices (biological fluids, emulsions, gels, etc.); 3. Designing and implementing signal generation and detection methods for the quantitative endotoxin measurement; 4. Planning assay prototypes to be developed and validated for commercial purposes. ENDONANO will train 5 PhD students in an overarching training programme that will include training-by-research, courses of technical, scientific, and transferrable skills, active participation to public scientific events, and intense intersectoral networking. The ENDONANO consortium encompasses an academic institution with strong expertise in inflammation and advanced biosensing, a young SME with top expertise in nanotechnology and use of nanoparticles for modulating bacterial functions, and 3 Participant Organisations (1 University and 2 companies). All have proven experience in higher education and training, and are endowed with state-of-the art scientific and technical expertise and infrastructures.
Tatsächlicher Beginn/ -es Ende1/01/1931/12/22