When investigating the physical principles of tissue growth on the cellular and multicellular level we need to explore the micromechanical and biochemical properties and dynamics on a micrometer length scale. I want to understand the tricks that nature uses to generate complex shapes and further to link the findings to the larger length scale of tissue development. Especially in the context of bone growth, remodeling and mineralization much is to learn about the fundamental connections between simple physical principles and the biology of tissue formation.