Personal profile
Research interests
Driven by the question how malignant hematopoietic cells occupy and modify bone marrow niches to establish a tumor protecting and promoting microenvironment, integrin-mediated leukemic cell adhesion and signaling have been the focus of my research.
Collaborations and top research areas from the last five years
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AIDIP: AI in digital pathology
Fortelny, N. (Principal Investigator), Aberger, F. (Co-Investigator), Krenn, P. (Co-Investigator) & Sotlar, K. (Co-Investigator)
1/01/26 → 31/12/28
Project: Research
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spaXio: Spatial Cross-Talk in Immuno-Oncology
Schmidt-Arras, D. (Principal Investigator), Krenn, P. (Co-Investigator) & Amend, D. (Co-Investigator)
1/10/25 → 30/09/29
Project: Research
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TARGET MPN: Targeting Kindlin-3-mediated integrin activation and signaling to eradicate persistent MPN clones
Krenn, P. (Principal Investigator) & Lankes, D. (Co-Investigator)
1/07/24 → 30/06/28
Project: Research
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Novel Inhibitors: Novel Inhibitors targeting oncogenic Hedgehog/GLI signaling
Aberger, F. (Principal Investigator), Krenn, P. (Co-Investigator) & Aichberger, S. K. (Co-Investigator)
1/09/23 → 31/12/24
Project: Research
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Selective EV Protein Sorting and Pathway Perturbation in AML Upon Synergistic FLT3 and Hedgehog Pathway Inhibition
Blöchl, C., Blümel, G., Wolf, M., Regl, C., Binder, H.-M., Tesanovic, S., Lankes, D., Maeding, N., Krenn, P. W., Strunk, D., Aberger, F. & Huber, C. G., Sept 2025, In: Journal of Extracellular Vesicles. 14, 9, p. e70163 e70163.Research output: Contribution to journal › Article › peer-review
Open Access -
High Efficiency Lentiviral Transduction of Colon Organoids Using Reversible 2D/3D Culture Techniques.
Rathje, F., Sykora, M. M., Aberger, F. & Krenn, P. W., 1 Apr 2025, In: Methods in Molecular Biology. 2905, p. 245-254 10 p.Research output: Contribution to journal › Article › peer-review
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Cooperative Hedgehog/GLI and JAK/STAT signaling drives immunosuppressive tryptophan/kynurenine metabolism via synergistic induction of IDO1 in skin cancer
Elmer, D. P., Stockmaier, G., Grund-Gröschke, S., Strobl, V., Dang, H.-H., Wiederstein, M., Licha, D., Strobl, A., Eglseer, A., Sternberg, C., Tesanovic, S., Gruber, W., Wolff, F., Moriggl, R., Risch, A., Reischl, R., Huber, C. G., Krenn, P. W., Fortelny, N. & Horejs-Hoeck, J. & 1 others, , 17 Feb 2025, In: Cell Communication and Signaling. 23, 1, p. 91 91.Research output: Contribution to journal › Article › peer-review
Open Access -
Inhibition of NLRP3 enhances pro-apoptotic effects of FLT3 inhibition in AML
Sieberer, H., Luciano, M., Amend, D., Blöchl, C., Eglseer, A., Steinkellner, A., Rieser, S., Andosch, A., Steiner, P., Hummer, L., Krenn, P. W., Dang, H.-H., Huber, C. G., Aberger, F., Neuper, T. & Horejs-Hoeck, J., 28 Jan 2025, In: Cell Communication and Signaling. 23, 1, p. 53 53.Research output: Contribution to journal › Article › peer-review
Open Access -
ADP-heptose attenuates Helicobacter pylori-induced dendritic cell activation
Neuper, T., Frauenlob, T., Dang, H.-H., Krenn, P. W., Posselt, G., Regl, C., Fortelny, N., Schäpertöns, V., Unger, M. S., Üblagger, G., Neureiter, D., Mühlbacher, I., Weitzendorfer, M., Singhartinger, F., Emmanuel, K., Huber, C. G., Wessler, S., Aberger, F. & Horejs-Hoeck, J., 17 Sept 2024, In: Gut Microbes. 16, 1, p. 2402543Research output: Contribution to journal › Article › peer-review
Open Access
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The effect of the NLRP3 inflammasome on EV secretion in AML
Amend, D. (Speaker), Sieberer, H. (Speaker), Luciano, M. (Speaker), Albu, T. R. (Speaker), Krenn, P. (Speaker), Vetter, J. (Speaker), Greil, R. (Speaker), Aberger, F. (Speaker) & Horejs-Höck, J. (Speaker)
5 Nov 2025 → 7 Nov 2025Activity: Talk or presentation › Poster presentation › science to science / art to art
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ADP-heptose attenuates Helicobacter pylori-induced dendritic cell activation
Neuper, T. (Speaker), Frauenlob, T. (Speaker), Dang, H.-H. (Speaker), Krenn, P. (Speaker), Posselt, G. B. (Speaker), Regl, C. (Speaker), Fortelny, N. (Speaker), Schäpertöns, V. (Speaker), Unger, M. S. (Speaker), Üblagger, G. L. (Speaker), Neureiter, D. (Speaker), Mühlbacher, I. (Speaker), Weitzendorfer, M. (Speaker), Singhartinger, F. (Speaker), Emmanuel, K. (Speaker), Huber, C. (Speaker), Weßler, S. (Speaker), Aberger, F. (Speaker) & Horejs-Höck, J. (Speaker)
17 Aug 2025 → 22 Aug 2025Activity: Talk or presentation › Poster presentation › science to science / art to art
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The NLRP3/eIF2 axis in acute myeloid leukemia
Sieberer, H. (Speaker), Luciano, M. (Speaker), Amend, D. (Speaker), Krenn, P. (Speaker), Vetter, J. (Speaker), Blöchl, C. (Speaker), Neuper, T. (Speaker), Dang, H.-H. (Speaker), Bauer, R. (Speaker), Andosch, A. (Speaker), Greil, R. (Speaker), Huber, C. (Speaker), Aberger, F. (Speaker) & Horejs-Höck, J. (Speaker)
17 Aug 2025 → 22 Aug 2025Activity: Talk or presentation › Poster presentation › science to science / art to art
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GLI-YAP interactions in basal cell carcinoma promote immune evasion by regulating the spatial distribution of immune responses.
Krenn, P. (Speaker), Stockmaier, G. (Speaker), Varkhande, S. (Speaker), Dang, H.-H. (Speaker), Sharma, A. (Speaker), Elmer, D. P. (Speaker), Steiner, M. (Speaker), Zaborsky, N. (Speaker), Neureiter, D. (Speaker), Greil, R. (Speaker), Horejs-Höck, J. (Speaker), Fortelny, N. (Speaker), Gratz, I. K. (Speaker) & Aberger, F. (Speaker)
12 Dec 2024Activity: Talk or presentation › Poster presentation › science to science / art to art
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Characterizing and disrupting leukemic stem cell interactions with their supportive microenvironment
Krenn, P. (Speaker)
29 Nov 2024Activity: Talk or presentation › Oral presentation › science to science / art to art
Press/Media
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Forscher der Universität Salzburg erhalten Millionen für Kampf gegen Krebs
Schmidt-Arras, D., Krenn, P. & Horejs-Höck, J.
5/04/25
1 item of Media coverage
Press/Media