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  • Josef Laimer
  • Markus Wiederstein
2020

A hybrid of two major Blomia tropicalis allergens as an allergy vaccine candidate

da Silva, E. S., Aglas, L., Pinheiro, C. S., de Andrade Belitardo, E. M. M., Silveira, E. F., Huber, S., Torres, R. T., Wallner, M., Briza, P., Lackner, P., Laimer, J., Pacheco, L. G. C., Cruz, Á. A., Alcântara-Neves, N. M. & Ferreira, F., 1 Jul 2020, In : Clinical and Experimental Allergy. 50, 7, p. 835-847 13 p.

Research output: Contribution to journalArticle

Retinoic acid-loading of the major birch pollen allergen Bet v 1 may improve specific allergen immunotherapy: In silico, in vitro and in vivo data in BALB/c mice

Hufnagl, K., Afify, S. M., Braun, N., Wagner, S., Wallner, M., Hauser, M., Wiederstein, M., Gadermaier, G., Wildner, S., Redegeld, F. A., Blokhuis, B. R., Hofstetter, G., Pali-Schoell, I., Roth-Walter, F., Pacios, L. F. & Jensen-Jarolim, E., 16 Apr 2020, In : Allergy: European Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalLetter

Open Access
Open Access
2019

Binding of vitamin D3 to the major birch pollen allergen Bet v 1 attenuates its allergenic capacity

Hufnagl, K., Kromp, L., Bianchini, R., Wiederstein, M., Redegeld, F., Hofstetter, G., Roth-Walter, F., F.Pacios, L. & Jensen-Jarolim, E., 2019.

Research output: Contribution to conferencePoster

Rational Design, Structure-Activity Relationship, and Immunogenicity of Hypoallergenic Pru p 3 Variants

Eichhorn, S., Hörschläger, A., Steiner, M., Laimer, J., Jensen, B. M., Versteeg, S. A., Pablos, I., Briza, P., Jongejan, L., Rigby, N., Asturias, J. A., Portolés, A., Fernandez-Rivas, M., Papadopoulos, N. G., Mari, A., Poulsen, L. K., Lackner, P., van Ree, R., Ferreira, F. & Gadermaier, G., Sep 2019, In : Molecular Nutrition and Food Research. 63, 18, p. 1-10 1900336.

Research output: Contribution to journalArticle

Open Access

Retinoic acid determines the allergenicity of the major birch pollen allergen Bet v 1 in vitro and in vivo

Hufnagl, K., Afify, S., Braun, N., Wagner, S., Wiederstein, M., Hofstetter, G., Pali-Schoell, I., Roth-Walter, F., Pacios, L. F. & Jensen-Jarolim, E., Aug 2019, In : Allergy: European Journal of Allergy and Clinical Immunology. 74, p. 335-336

Research output: Contribution to journalMeeting Abstract

Structure Based Prediction of MHC II Binding Peptides

Laimer, J., Wiederstein, M. & Lackner, P., 22 Jul 2019.

Research output: Contribution to conferencePoster

The cell wall PAC (Pro-rich, Arabinogalactan proteins, conserved Cysteines) domain-proteins are conserved in the green lineage

Nguyen-Kim, H., San Clemente, H., Kolkas, H., Laimer, J., Lackner, P., Gadermaier, G., Dunand, C. & Jamet, E., 2019.

Research output: Contribution to conferenceAbstract

2018

Synergistic cross-talk of hedgehog and interleukin-6 signaling drives growth of basal cell carcinoma

Sternberg, C., Gruber, W., Eberl, M., Tesanovic, S., Stadler, M., Elmer, D. P., Schlederer, M., Grund, S., Roos, S., Wolff, F., Kaur, S., Mangelberger, D., Lehrach, H., Hache, H., Wierling, C., Laimer, J., Lackner, P., Wiederstein, M., Kasper, M., Risch, A. & 4 others, Petzelbauer, P., Moriggl, R., Kenner, L. & Aberger, F., 1 Dec 2018, In : International Journal of Cancer. 143, 11, p. 2943-2954

Research output: Contribution to journalArticle

2017

Characterization of a Phl p 6 mutant with increased structural stability

Soh, W. T., Stubenvoll, S., Brückl, A., Scheiblhofer, S., Laimer, J., Lackner, P., Thalhamer, J., Brandstetter, H. & Weiss, R., 17 Jun 2017.

Research output: Contribution to conferencePoster

Influence of protein fold stability on immunogenicity and its implications for vaccine design

Scheiblhofer, S., Laimer, J., Hernandez, Y. J. M., Weiss, R. & Thalhamer, J., 2017, In : Expert Review of Vaccines.

Research output: Contribution to journalArticle

Influence of protein fold stability on immunogenicity and its implications for vaccine design

Scheiblhofer, S., Laimer, J., Machado, Y., Weiss, R. & Thalhamer, J., 2017, In : Expert Review of Vaccines. 16, 5, p. 479-489

Research output: Contribution to journalReview article

Tackling Bet v 1 and associated food allergies with a single hybrid protein

Hofer, H., Asam, C., Hauser, M., Nagl, B., Laimer, J., Himly, M., Briza, P., Ebner, C., Lang, R., Hawranek, T., Bohle, B., Lackner, P., Ferreira, F. & Wallner, M., 2017, In : Journal of Allergy and Clinical Immunology. 140, 2, p. 525-533

Research output: Contribution to journalArticle

2016

MAESTROweb: a web server for structure based protein stability prediction: a web server for structure-based protein stability prediction

Laimer, J., Hiebl-Flach, J., Lengauer, D. & Lackner, P., 1 May 2016, In : Bioinformatics. 32, 9, p. 1414-6 3 p.

Research output: Contribution to journalArticle

Open Access

Nanoparticle-allergen interactions mediate human allergic responses: Protein corona characterization and cellular responses: protein corona characterization and cellular responses

Radauer-Preiml, I., Andosch, A., Hawranek, T., Lütz-Meindl, U., Wiederstein, M., Horejs-Höck, J., Himly, M., Boyles, M. & Duschl, A., 16 Jan 2016, In : Particle and Fibre Toxicology. 13, 1, p. 1-15 3.

Research output: Contribution to journalArticle

Open Access

The Hyper-Allergenic Isoform Bet v 1a of the Major Birch Pollen Allergen Displays Reduced Allergenic Potential after Binding of Retinoic Acid

Hufnagl, K., Wagner, S., F.Pacios, L., Wallner, M., Wiederstein, M., Hofstetter, G., Roth-Walter, F. & Jensen-Jarolim, E., 2016.

Research output: Contribution to conferencePoster

2015

MAESTRO - multi agent stability prediction upon point mutations

Laimer, J., Hofer, H., Fritz, M., Wegenkittl, S. & Lackner, P., 16 Apr 2015, In : BMC Bioinformatics. 16, p. 1-13 13 p., 116.

Research output: Contribution to journalArticle

Open Access

Nanoparticle-allergen interactions mediate human allergic responses: protein corona characterization and cellular responses

Radauer-Preiml, I., Andosch, A., Hawranek, T., Luetz-Meindl, U., Wiederstein, M., Horejs-Hoeck, J., Himly, M., Boyles, M. S. P. & Duschl, A., 2015, In : Particle and Fibre Toxicology.

Research output: Contribution to journalArticle

2014

Immunological characterization of a Pru p 3 proline variant for treatment of LTP-related peach allergy

Gadermaier, G., Laimer, J., Ocampo, I. M. P., Eichhorn, S. P. & Ferreira, F., 2014.

Research output: Contribution to conferenceAbstract

Structure-Based Characterization of Multiprotein Complexes

Wiederstein, M., Gruber, M., Frank, K., Melo, F. & Sippl, M. J., 8 Jul 2014, In : Structure. 22, 7, p. 1063-1070 8 p.

Research output: Contribution to journalArticle

2013

Automated clustering of protein structures and complexes

J.Sippl, M., Frank, K., Gruber, M. & Wiederstein, M., 2013.

Research output: Contribution to conferencePoster

Comprehensive analysis of alterations in the miRNome in response to photodynamic treatment

Bach, D., Fuereder, J., Karbiener, M., Scheideler, M., Lena, R. A., Neureiter, D., Kemmerling, R., Dietze, O., Wiederstein, M., Berr, F., Plätzer, K., Kiesslich, T. & Pichler, M., 5 Mar 2013, In : Journal of Photochemistry and Photobiology B: Biology. 120, p. 74-81 8 p.

Research output: Contribution to journalArticle

Development of a hypoallergenic and immunogenic Pru p 3 proline variant for treatment of peach allergy

Eichhorn, S. P., Steiner, M., Laimer, J., Lackner, P., Zuidmeer-Jongejan, L., Briza, P., Mari, A., Ree, R. V., Ferreira, F. & Gadermaier, G., 2013.

Research output: Contribution to conferenceAbstract

D-Light on promoters: a client-server system for the analysis and visualization of cis-regulatory elements

Laimer, J., Zuzan, C. J., Ehrenberger, T., Freudenberger, M., Gschwandtner, S., Lebherz, C. & Lackner, P., 24 Apr 2013, In : BMC Bioinformatics. 14, p. 1-8 140.

Research output: Contribution to journalArticle

Open Access

Structural and functional collection of biological units

J.Sippl, M., Frank, K., Wiederstein, M. & Gruber, M., 2013.

Research output: Contribution to conferencePoster

2012

Detection of spatial correlations in protein structures and molecular complexes

Sippl, M. J. & Wiederstein, M., 4 Apr 2012, In : Structure. 20, 4, p. 718-728 11 p.

Research output: Contribution to journalArticle

Effective techniques for protein structure mining

Suhrer, S. J., Gruber, M., Wiederstein, M. & Sippl, M. J., 2012, In : Methods in molecular biology (Clifton, N.J.). 857, p. 33-54 22 p.

Research output: Contribution to journalArticle

2011

Leben nach Plan - Utopien in den Biowissenschaften

Translated title of the contribution: Leben nach Plan - Utopien in den BiowissenschaftenWiederstein, M., 2011, Europäische Projektkultur als Beitrag zur Rationalisierung des Rechts. ÖCG, p. 613-618 (Tagungsband des Internationalen Rechtsinformatik Symposions IRIS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2009

COPS--a novel workbench for explorations in fold space

Suhrer, S. J., Wiederstein, M., Gruber, M. & Sippl, M. J., Jul 2009, In : Nucleic Acids Research. 37, Web Server issue, p. W539-44

Research output: Contribution to journalArticle

COPS—a novel workbench for explorations in fold space

Suhrer, S., Wiederstein, M., Gruber, M. & Sippl, M. J., 2009, In : Nucleic Acids Research. p. W539-W544

Research output: Contribution to journalArticle

2008

A Discrete View on Fold Space

Sippl, M. J., Suhrer, S. J., Gruber, M., Wiederstein, M. & Suhrer, S., 15 Mar 2008, In : Bioinformatics. 24, 6, p. 870-871 2 p.

Research output: Contribution to journalArticle

A note on difficult structure alignment problems

Sippl, M. J. & Wiederstein, M., 1 Feb 2008, In : Bioinformatics. 24, 3, p. 426-7 2 p.

Research output: Contribution to journalArticle

2007

ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins

Wiederstein, M. & Sippl, M. J., 2007, In : Nucleic Acids Research. p. W407-W410

Research output: Contribution to journalArticle

QSCOP - SCOP quantified by structural relationships

Suhrer, S. J., Wiederstein, M. & Sippl, M. J., 15 Feb 2007, In : Bioinformatics. 23, 4, p. 513-514 2 p.

Research output: Contribution to journalArticle

2005

Protein sequence randomization: efficient estimation of protein stability using knowledge-based potentials

Wiederstein, M. & Sippl, M. J., 4 Feb 2005, In : Journal of Molecular Biology. 345, 5, p. 1199-1212 13 p.

Research output: Contribution to journalArticle

2004

Directed in silico Mutagenesis

Wiederstein, M., Lackner, P., Kienberger, F. & Sippl, M. J., 2004, Evolutionary Methods in Biotechnology. Wiley-VCH, p. 153-175 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter in Book

2001

Assessment of the CASP4 Fold Recognition Category

Sippl, M. J., Lackner, P., Domingues, F. S., Prlic, A., Malik, R., Andreeva, A. & Wiederstein, M., 2001, In : Proteins: Structure, Function and Genetics. p. 55-67 13 p.

Research output: Contribution to journalArticle

2000

Characterization of novel proteins based on known protein structures

Koppensteiner, W. A., Lackner, P., Wiederstein, M. & Sippl, M. J., 3 Mar 2000, In : Journal of Molecular Biology. 296, 4, p. 1139-1152 14 p.

Research output: Contribution to journalArticle

1999

CASP3 prediction results for the fold recognition tool ProFIT

Wiederstein, M., Domingues, F. S., Koppensteiner, W. A., Jaritz, M., Prlic, A., Weichenberger, C., Flöckner, H., Lackner, P. & Sippl, M. J., 1999.

Research output: Contribution to conferencePoster

Sustained Performance of Knowledge-Based Potentials in Fold Recognition

Domingues, F. S., Koppensteiner, W. A., Jaritz, M., Prlic, A., Weichenberger, C., Wiederstein, M., Flöckner, H., Lackner, P. & Sippl, M. J., 1999, In : Proteins: Structure, Function and Genetics. p. 112-120

Research output: Contribution to journalArticle

The coverage of protein fold recognition

Koppensteiner, W. A., Wiederstein, M., Lackner, P. & Sippl, M. J., 1999.

Research output: Contribution to conferencePoster