A Comparative Endocrine Trans-Differentiation Approach to Pancreatic Ductal Adenocarcinoma Cells with Different EMT Phenotypes Identifies Quasi-Mesenchymal Tumor Cells as Those with Highest Plasticity

Paula M Schmidtlein; Clara Volz; Rüdiger Braun; Isabel Thürling; Olha Lapshyna; Ulrich F Wellner; Björn Konukiewitz; Hendrik Lehnert; Jens-Uwe Marquardt; Hendrik Ungefroren

doi:10.3390/cancers13184663

A Comparative Endocrine Trans-Differentiation Approach to Pancreatic Ductal Adenocarcinoma Cells with Different EMT Phenotypes Identifies Quasi-Mesenchymal Tumor Cells as Those with Highest Plasticity

Paula M Schmidtlein, Clara Volz, Rüdiger Braun, Isabel Thürling, Olha Lapshyna, Ulrich F Wellner, Björn Konukiewitz, Hendrik Lehnert, Jens-Uwe Marquardt, Hendrik Ungefroren

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Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	4663
Journal	Cancers
Volume	13
Issue number	18
DOIs	https://doi.org/10.3390/cancers13184663
Publication status	Published - 17 Sept 2021

Bibliographical note

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Keywords

Endocrine
Epithelial
Insulin
Pancreatic ductal adenocarcinoma
Pancreatic β cell
Plasticity
Quasi-mesenchymal
Transdifferentiation

Fields of Science and Technology Classification 2012

302 Clinical Medicine

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10.3390/cancers13184663

Cite this

Schmidtlein, P. M., Volz, C., Braun, R., Thürling, I., Lapshyna, O., Wellner, U. F., Konukiewitz, B., Lehnert, H., Marquardt, J.-U., & Ungefroren, H. (2021). A Comparative Endocrine Trans-Differentiation Approach to Pancreatic Ductal Adenocarcinoma Cells with Different EMT Phenotypes Identifies Quasi-Mesenchymal Tumor Cells as Those with Highest Plasticity. Cancers, 13(18), Article 4663. https://doi.org/10.3390/cancers13184663

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title = "A Comparative Endocrine Trans-Differentiation Approach to Pancreatic Ductal Adenocarcinoma Cells with Different EMT Phenotypes Identifies Quasi-Mesenchymal Tumor Cells as Those with Highest Plasticity",

keywords = "Endocrine, Epithelial, Insulin, Pancreatic ductal adenocarcinoma, Pancreatic β cell, Plasticity, Quasi-mesenchymal, Transdifferentiation",

author = "Schmidtlein, {Paula M} and Clara Volz and R{\"u}diger Braun and Isabel Th{\"u}rling and Olha Lapshyna and Wellner, {Ulrich F} and Bj{\"o}rn Konukiewitz and Hendrik Lehnert and Jens-Uwe Marquardt and Hendrik Ungefroren",

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year = "2021",

month = sep,

day = "17",

doi = "10.3390/cancers13184663",

language = "English",

volume = "13",

journal = "Cancers",

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Schmidtlein, PM, Volz, C, Braun, R, Thürling, I, Lapshyna, O, Wellner, UF, Konukiewitz, B, Lehnert, H, Marquardt, J-U & Ungefroren, H 2021, 'A Comparative Endocrine Trans-Differentiation Approach to Pancreatic Ductal Adenocarcinoma Cells with Different EMT Phenotypes Identifies Quasi-Mesenchymal Tumor Cells as Those with Highest Plasticity', Cancers, vol. 13, no. 18, 4663. https://doi.org/10.3390/cancers13184663

A Comparative Endocrine Trans-Differentiation Approach to Pancreatic Ductal Adenocarcinoma Cells with Different EMT Phenotypes Identifies Quasi-Mesenchymal Tumor Cells as Those with Highest Plasticity. / Schmidtlein, Paula M; Volz, Clara; Braun, Rüdiger et al.
In: Cancers, Vol. 13, No. 18, 4663, 17.09.2021.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - A Comparative Endocrine Trans-Differentiation Approach to Pancreatic Ductal Adenocarcinoma Cells with Different EMT Phenotypes Identifies Quasi-Mesenchymal Tumor Cells as Those with Highest Plasticity

AU - Schmidtlein, Paula M

AU - Volz, Clara

AU - Braun, Rüdiger

AU - Thürling, Isabel

AU - Lapshyna, Olha

AU - Wellner, Ulrich F

AU - Konukiewitz, Björn

AU - Lehnert, Hendrik

AU - Marquardt, Jens-Uwe

AU - Ungefroren, Hendrik

PY - 2021/9/17

Y1 - 2021/9/17

KW - Endocrine

KW - Epithelial

KW - Insulin

KW - Pancreatic ductal adenocarcinoma

KW - Pancreatic β cell

KW - Plasticity

KW - Quasi-mesenchymal

KW - Transdifferentiation

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U2 - 10.3390/cancers13184663

DO - 10.3390/cancers13184663

M3 - Article

C2 - 34572891

SN - 2072-6694

VL - 13

JO - Cancers

JF - Cancers

IS - 18

M1 - 4663

ER -

A Comparative Endocrine Trans-Differentiation Approach to Pancreatic Ductal Adenocarcinoma Cells with Different EMT Phenotypes Identifies Quasi-Mesenchymal Tumor Cells as Those with Highest Plasticity

Bibliographical note

Keywords

Fields of Science and Technology Classification 2012

Access to Document

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