Autocrine TGFβ1 Opposes Exogenous TGFβ1-Induced Cell Migration and Growth Arrest through Sustainment of a Feed-Forward Loop Involving MEK-ERK Signaling

Hendrik Ungefroren, Jessica Christl, Caroline Eiden, Ulrich F Wellner, Hendrik Lehnert, Jens-Uwe Marquardt

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number1357
Pages (from-to)1-16
Number of pages16
JournalCancers
Volume13
Issue number6
DOIs
Publication statusPublished - 17 Mar 2021

Bibliographical note

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.

Keywords

  • Autocrine regulation
  • Breast cancer
  • Cell growth
  • Extracellular-regulated kinase
  • Pancreatic cancer
  • SNAIL
  • Transforming growth factor β
  • WAF1
  • transforming growth factor &#946
  • autocrine regulation
  • cell growth
  • breast cancer
  • pancreatic cancer
  • extracellular-regulated kinase

Fields of Science and Technology Classification 2012

  • 302 Clinical Medicine

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