Drug Development for Target Ribosomal Protein rpL35/uL29 for Repair of LAMB3R635X in Rare Skin Disease Epidermolysis Bullosa

Adriana Rathner, Petr Rathner, Andreas Friedrich, Michael Wießner, Christian Manuel Kitzler, Jan Schernthaner, Thomas Karl, Jan Krauß, Friedrich Lottspeich, Werner Mewes, Helmut Hintner, Johann W Bauer, Michael Breitenbach, Norbert Müller, Hannelore Breitenbach-Koller, Jörg von Hagen

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)167-182
Number of pages16
JournalSkin Pharmacology and Physiology
Volume34
Issue number4
DOIs
Publication statusPublished - 2021

Bibliographical note

© 2021 S. Karger AG, Basel.

Keywords

  • Artesunate/chemistry
  • Atazanavir Sulfate/chemistry
  • Cell Adhesion Molecules/genetics
  • Epidermolysis Bullosa, Junctional/genetics
  • Humans
  • Molecular Docking Simulation
  • Protein Binding/physiology
  • RNA, Messenger/metabolism
  • Ribosomal Proteins/metabolism
  • Skin/pathology
  • Skin Physiological Phenomena
  • Mutations
  • Epidermolysis bullosa
  • Drug development
  • Skin models
  • Premature termination codon
  • Ribosomal protein L35
  • mutations

Fields of Science and Technology Classification 2012

  • 302 Clinical Medicine
  • 304 Medical Biotechnology
  • 106 Biology

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