Effective techniques for protein structure mining

Stefan J Suhrer, Markus Gruber, Markus Wiederstein, Manfred J Sippl

    Research output: Contribution to journalArticle

    Abstract

    Retrieval and characterization of protein structure relationships are instrumental in a wide range of tasks in structural biology. The classification of protein structures (COPS) is a web service that provides efficient access to structure and sequence similarities for all currently available protein structures. Here, we focus on the application of COPS to the problem of template selection in homology modeling.

    Original languageEnglish
    Pages (from-to)33-54
    Number of pages22
    JournalMethods in molecular biology (Clifton, N.J.)
    Volume857
    DOIs
    Publication statusPublished - 2012

    Fields of Science and Technology Classification 2012

    • 106 Biology

    Keywords

    • Amino Acid Sequence
    • Data Mining/methods
    • Databases, Protein
    • Models, Molecular
    • Molecular Sequence Data
    • Protein Conformation
    • Proteins/chemistry
    • Structural Homology, Protein

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