Fragment-Based Design, Synthesis, and Characterization of Aminoisoindole-Derived Furin Inhibitors

Roman W. Lange, Konstantin Bloch, Miriam Ruth Heindl, Jan Wollenhaupt, Manfred S. Weiss, Hans Brandstetter, Gerhard Klebe, Franco H. Falcone, Eva Boettcher-Friebertshaeuser, Sven O. Dahms, Torsten Steinmetzer

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article numbere202400057
Number of pages15
JournalCHEMMEDCHEM
Volume19
Issue number9
DOIs
Publication statusPublished - 2 May 2024

Bibliographical note

Publisher Copyright:
© 2024 The Authors. ChemMedChem published by Wiley-VCH GmbH.

Keywords

  • Crystal structure analysis
  • Fragment screening
  • Furin inhibitors
  • Proprotein convertases
  • Proteolytic activation of viruses
  • crystal structure analysis
  • proteolytic activation of viruses
  • proprotein convertases
  • furin inhibitors
  • fragment screening

Fields of Science and Technology Classification 2012

  • 104 Chemistry
  • 106 Biology

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