Impacts of rapid mass vaccination against SARS-CoV2 in an early variant of concern hotspot

Jörg Manfred Paetzold; Janine Kimpel; Katie Bates; Michael Hummer; Florian Krammer; Dorothee von Laer; Hannes Winner

doi:10.1038/s41467-022-28233-8

Impacts of rapid mass vaccination against SARS-CoV2 in an early variant of concern hotspot

Jörg Manfred Paetzold, Janine Kimpel, Katie Bates, Michael Hummer, Florian Krammer, Dorothee von Laer, Hannes Winner

Economics

Research output: Contribution to journal › Article › peer-review

Abstract

We study the real-life effect of an unprecedented rapid mass vaccination campaign. Following a large outbreak of the Beta variant in the district of Schwaz/Austria, 100,000 doses of BNT162b2 (Pfizer/BioNTech) were procured to mass vaccinate the entire adult population of the district between the 11th and 16th of March 2021. This made the district the first widely inoculated region in Europe. We examine the effect of this campaign on the number of infections, cases of variants of concern, hospital and ICU admissions. We compare Schwaz with (i) a control group of highly similar districts, and (ii) with populations residing in municipalities along the border of Schwaz which were just excluded from the campaign. We find large and significant decreases for all outcomes after the campaign. Our results suggest that rapid mass vaccination is an effective tool to curb the spread of SARS-CoV-2.

Original language	English
Article number	612
Number of pages	7
Journal	Nature Communications
Volume	13
Issue number	1
DOIs	https://doi.org/10.1038/s41467-022-28233-8
Publication status	Published - 1 Feb 2022

Bibliographical note

Publisher Copyright:
© 2022, The Author(s).

Keywords

Adult
Austria/epidemiology
BNT162 Vaccine/administration & dosage
COVID-19/epidemiology
Hospitalization/statistics & numerical data
Humans
Intensive Care Units/statistics & numerical data
Mass Vaccination
Middle Aged
Retrospective Studies
SARS-CoV-2/genetics

Fields of Science and Technology Classification 2012

303 Health Sciences

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10.1038/s41467-022-28233-8Licence: CC BY

Cite this

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abstract = "We study the real-life effect of an unprecedented rapid mass vaccination campaign. Following a large outbreak of the Beta variant in the district of Schwaz/Austria, 100,000 doses of BNT162b2 (Pfizer/BioNTech) were procured to mass vaccinate the entire adult population of the district between the 11th and 16th of March 2021. This made the district the first widely inoculated region in Europe. We examine the effect of this campaign on the number of infections, cases of variants of concern, hospital and ICU admissions. We compare Schwaz with (i) a control group of highly similar districts, and (ii) with populations residing in municipalities along the border of Schwaz which were just excluded from the campaign. We find large and significant decreases for all outcomes after the campaign. Our results suggest that rapid mass vaccination is an effective tool to curb the spread of SARS-CoV-2.",

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Impacts of rapid mass vaccination against SARS-CoV2 in an early variant of concern hotspot

Abstract

Bibliographical note

Keywords

Fields of Science and Technology Classification 2012

Access to Document

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Cite this