Salmonella enterica Serovar Typhimurium Induces NAIP/NLRC4- and NLRP3/ASC-Independent, Caspase-4-Dependent Inflammasome Activation in Human Intestinal Epithelial Cells

Nawar Naseer; Jenna Zhang; Renate Bauer; David A Constant; Timothy J Nice; Igor E Brodsky; Isabella Rauch; Sunny Shin

doi:10.1128/iai.00663-21

Salmonella enterica Serovar Typhimurium Induces NAIP/NLRC4- and NLRP3/ASC-Independent, Caspase-4-Dependent Inflammasome Activation in Human Intestinal Epithelial Cells

Nawar Naseer, Jenna Zhang, Renate Bauer, David A Constant, Timothy J Nice, Igor E Brodsky, Isabella Rauch, Sunny Shin

Animal Services

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	e0066321
Journal	Infection and immunity
Volume	90
Issue number	7
DOIs	https://doi.org/10.1128/iai.00663-21
Publication status	Published - 21 Jul 2022

Bibliographical note

Publisher Copyright:
© 2022 American Society for Microbiology. All Rights Reserved.

Keywords

Animals
Apoptosis Regulatory Proteins
CARD Signaling Adaptor Proteins
Caco-2 Cells
Calcium-Binding Proteins
Caspases, Initiator
Epithelial Cells/metabolism
Humans
Inflammasomes/metabolism
Mice
NLR Family, Pyrin Domain-Containing 3 Protein/metabolism
Neuronal Apoptosis-Inhibitory Protein
Salmonella typhimurium
Serogroup
Salmonella
NLRC4
human innate immunity
ASC
intestinal epithelial cell
inflammasome
CASP4
NLRP3
NAIP

Fields of Science and Technology Classification 2012

106 Biology

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10.1128/iai.00663-21

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@article{cb5f85bbee5544af9daa484a03e23833,

title = "Salmonella enterica Serovar Typhimurium Induces NAIP/NLRC4- and NLRP3/ASC-Independent, Caspase-4-Dependent Inflammasome Activation in Human Intestinal Epithelial Cells",

keywords = "Animals, Apoptosis Regulatory Proteins, CARD Signaling Adaptor Proteins, Caco-2 Cells, Calcium-Binding Proteins, Caspases, Initiator, Epithelial Cells/metabolism, Humans, Inflammasomes/metabolism, Mice, NLR Family, Pyrin Domain-Containing 3 Protein/metabolism, Neuronal Apoptosis-Inhibitory Protein, Salmonella typhimurium, Serogroup, Salmonella, NLRC4, human innate immunity, ASC, intestinal epithelial cell, inflammasome, CASP4, NLRP3, NAIP",

author = "Nawar Naseer and Jenna Zhang and Renate Bauer and Constant, {David A} and Nice, {Timothy J} and Brodsky, {Igor E} and Isabella Rauch and Sunny Shin",

year = "2022",

month = jul,

day = "21",

doi = "10.1128/iai.00663-21",

language = "English",

volume = "90",

pages = "e0066321",

journal = "Infection and immunity",

issn = "0019-9567",

publisher = "American Society for Microbiology",

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TY - JOUR

T1 - Salmonella enterica Serovar Typhimurium Induces NAIP/NLRC4- and NLRP3/ASC-Independent, Caspase-4-Dependent Inflammasome Activation in Human Intestinal Epithelial Cells

AU - Naseer, Nawar

AU - Zhang, Jenna

AU - Bauer, Renate

AU - Constant, David A

AU - Nice, Timothy J

AU - Brodsky, Igor E

AU - Rauch, Isabella

AU - Shin, Sunny

PY - 2022/7/21

Y1 - 2022/7/21

KW - Animals

KW - Apoptosis Regulatory Proteins

KW - CARD Signaling Adaptor Proteins

KW - Caco-2 Cells

KW - Calcium-Binding Proteins

KW - Caspases, Initiator

KW - Epithelial Cells/metabolism

KW - Humans

KW - Inflammasomes/metabolism

KW - Mice

KW - NLR Family, Pyrin Domain-Containing 3 Protein/metabolism

KW - Neuronal Apoptosis-Inhibitory Protein

KW - Salmonella typhimurium

KW - Serogroup

KW - Salmonella

KW - NLRC4

KW - human innate immunity

KW - ASC

KW - intestinal epithelial cell

KW - inflammasome

KW - CASP4

KW - NLRP3

KW - NAIP

UR - http://www.scopus.com/inward/record.url?scp=85134855250&partnerID=8YFLogxK

U2 - 10.1128/iai.00663-21

DO - 10.1128/iai.00663-21

M3 - Article

C2 - 35678562

SN - 0019-9567

VL - 90

SP - e0066321

JO - Infection and immunity

JF - Infection and immunity

IS - 7

ER -

Salmonella enterica Serovar Typhimurium Induces NAIP/NLRC4- and NLRP3/ASC-Independent, Caspase-4-Dependent Inflammasome Activation in Human Intestinal Epithelial Cells

Bibliographical note

Keywords

Fields of Science and Technology Classification 2012

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