Selectivity and Resolving Power of Hydrophobic Interaction Chromatography Targeting the Separation of Monoclonal Antibody Variants

Raphael Ewonde Ewonde; Katharina Böttinger; Jelle De Vos; Nico Lingg; Alois Jungbauer; Christopher A. Pohl; Christian G. Huber; Gert Desmet; Sebastiaan Eeltink

doi:10.1021/acs.analchem.3c04011

Selectivity and Resolving Power of Hydrophobic Interaction Chromatography Targeting the Separation of Monoclonal Antibody Variants

Raphael Ewonde Ewonde, Katharina Böttinger, Jelle De Vos, Nico Lingg, Alois Jungbauer, Christopher A. Pohl, Christian G. Huber, Gert Desmet, Sebastiaan Eeltink

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1121-1128
Number of pages	8
Journal	Analytical Chemistry
Volume	96
Issue number	3
DOIs	https://doi.org/10.1021/acs.analchem.3c04011
Publication status	Published - 8 Jan 2024

Bibliographical note

Publisher Copyright:
© 2024 The Authors. Published by American Chemical Society.

Keywords

Antibodies, Monoclonal/chemistry
Chlorides
Chromatography
Hydrophobic and Hydrophilic Interactions
Peptides
Trastuzumab

Fields of Science and Technology Classification 2012

104 Chemistry
106 Biology

Access to Document

10.1021/acs.analchem.3c04011

Cite this

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title = "Selectivity and Resolving Power of Hydrophobic Interaction Chromatography Targeting the Separation of Monoclonal Antibody Variants",

keywords = "Antibodies, Monoclonal/chemistry, Chlorides, Chromatography, Hydrophobic and Hydrophilic Interactions, Peptides, Trastuzumab",

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AU - Ewonde, Raphael Ewonde

AU - Böttinger, Katharina

AU - De Vos, Jelle

AU - Lingg, Nico

AU - Jungbauer, Alois

AU - Pohl, Christopher A.

AU - Huber, Christian G.

AU - Desmet, Gert

AU - Eeltink, Sebastiaan

PY - 2024/1/8

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KW - Chlorides

KW - Chromatography

KW - Hydrophobic and Hydrophilic Interactions

KW - Peptides

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U2 - 10.1021/acs.analchem.3c04011

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JO - Analytical Chemistry

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Selectivity and Resolving Power of Hydrophobic Interaction Chromatography Targeting the Separation of Monoclonal Antibody Variants

Bibliographical note

Keywords

Fields of Science and Technology Classification 2012

Access to Document

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Cite this