“Small is beautiful” – Examining reliable determination of low-abundant therapeutic antibody glycovariants

Katharina Böttinger; Christof Regl; Veronika Schäpertöns; Erdmann Rapp; Therese Wohlschlager; Christian G. Huber

doi:10.1016/j.jpha.2024.100982

“Small is beautiful” – Examining reliable determination of low-abundant therapeutic antibody glycovariants

Katharina Böttinger, Christof Regl, Veronika Schäpertöns, Erdmann Rapp, Therese Wohlschlager, Christian G. Huber

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	100982
Journal	Journal of Pharmaceutical Analysis
Volume	14
Issue number	10
DOIs	https://doi.org/10.1016/j.jpha.2024.100982
Publication status	Published - Oct 2024

Bibliographical note

Publisher Copyright:
© 2024 The Author(s)

Keywords

Abundance profiling
Data integration
Glycosylation
Mass spectrometry
Minor glycovariants
Monoclonal antibodies
Multi-level analysis

Fields of Science and Technology Classification 2012

104 Chemistry
106 Biology

Access to Document

10.1016/j.jpha.2024.100982

Cite this

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title = "“Small is beautiful” – Examining reliable determination of low-abundant therapeutic antibody glycovariants",

keywords = "Abundance profiling, Data integration, Glycosylation, Mass spectrometry, Minor glycovariants, Monoclonal antibodies, Multi-level analysis",

author = "Katharina B{\"o}ttinger and Christof Regl and Veronika Sch{\"a}pert{\"o}ns and Erdmann Rapp and Therese Wohlschlager and Huber, {Christian G.}",

note = "Publisher Copyright: {\textcopyright} 2024 The Author(s)",

year = "2024",

month = oct,

doi = "10.1016/j.jpha.2024.100982",

language = "English",

volume = "14",

journal = "Journal of Pharmaceutical Analysis",

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publisher = "Xi'an Jiaotong University",

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T1 - “Small is beautiful” – Examining reliable determination of low-abundant therapeutic antibody glycovariants

AU - Böttinger, Katharina

AU - Regl, Christof

AU - Schäpertöns, Veronika

AU - Rapp, Erdmann

AU - Wohlschlager, Therese

AU - Huber, Christian G.

PY - 2024/10

Y1 - 2024/10

KW - Abundance profiling

KW - Data integration

KW - Glycosylation

KW - Mass spectrometry

KW - Minor glycovariants

KW - Monoclonal antibodies

KW - Multi-level analysis

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UR - https://www.mendeley.com/catalogue/2ea9c49b-939d-305f-ab6c-967b2d45e95c/

U2 - 10.1016/j.jpha.2024.100982

DO - 10.1016/j.jpha.2024.100982

M3 - Article

SN - 2095-1779

VL - 14

JO - Journal of Pharmaceutical Analysis

JF - Journal of Pharmaceutical Analysis

IS - 10

M1 - 100982

ER -

“Small is beautiful” – Examining reliable determination of low-abundant therapeutic antibody glycovariants

Bibliographical note

Keywords

Fields of Science and Technology Classification 2012

Access to Document

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Cite this