The Quasimesenchymal Pancreatic Ductal Epithelial Cell Line PANC-1-A Useful Model to Study Clonal Heterogeneity and EMT Subtype Shifting

Hendrik Ungefroren; Isabel Thürling; Benedikt Färber; Tanja Kowalke; Tanja Fischer; Leonardo Vinícius Monteiro De Assis; Rüdiger Braun; Darko Castven; Henrik Oster; Björn Konukiewitz; Ulrich Friedrich Wellner; Hendrik Lehnert; Jens-Uwe Marquardt

doi:10.3390/cancers14092057

The Quasimesenchymal Pancreatic Ductal Epithelial Cell Line PANC-1-A Useful Model to Study Clonal Heterogeneity and EMT Subtype Shifting

Hendrik Ungefroren, Isabel Thürling, Benedikt Färber, Tanja Kowalke, Tanja Fischer, Leonardo Vinícius Monteiro De Assis, Rüdiger Braun, Darko Castven, Henrik Oster, Björn Konukiewitz, Ulrich Friedrich Wellner, Hendrik Lehnert, Jens-Uwe Marquardt

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Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	2057
Journal	Cancers
Volume	14
Issue number	9
DOIs	https://doi.org/10.3390/cancers14092057
Publication status	Published - 19 Apr 2022

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Publisher Copyright:
© 2022 by the author. Licensee MDPI, Basel, Switzerland.

Keywords

EMT
MET
PANC‐1
epithelial–mesenchymal plasticity
intratumoral heterogeneity
pancreatic ductal adenocarcinoma
phenotype
proinflammatory cytokines
transdifferentiation
transforming growth factor β
transforming growth factor beta
epithelial-mesenchymal plasticity
PANC-1

Fields of Science and Technology Classification 2012

302 Clinical Medicine

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10.3390/cancers14092057

Cite this

Ungefroren, H., Thürling, I., Färber, B., Kowalke, T., Fischer, T., De Assis, L. V. M., Braun, R., Castven, D., Oster, H., Konukiewitz, B., Wellner, U. F., Lehnert, H., & Marquardt, J.-U. (2022). The Quasimesenchymal Pancreatic Ductal Epithelial Cell Line PANC-1-A Useful Model to Study Clonal Heterogeneity and EMT Subtype Shifting. Cancers, 14(9), Article 2057. https://doi.org/10.3390/cancers14092057

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keywords = "EMT, MET, PANC‐1, epithelial–mesenchymal plasticity, intratumoral heterogeneity, pancreatic ductal adenocarcinoma, phenotype, proinflammatory cytokines, transdifferentiation, transforming growth factor β, transforming growth factor beta, epithelial-mesenchymal plasticity, PANC-1",

author = "Hendrik Ungefroren and Isabel Th{\"u}rling and Benedikt F{\"a}rber and Tanja Kowalke and Tanja Fischer and {De Assis}, {Leonardo Vin{\'i}cius Monteiro} and R{\"u}diger Braun and Darko Castven and Henrik Oster and Bj{\"o}rn Konukiewitz and Wellner, {Ulrich Friedrich} and Hendrik Lehnert and Jens-Uwe Marquardt",

note = "Publisher Copyright: {\textcopyright} 2022 by the author. Licensee MDPI, Basel, Switzerland.",

year = "2022",

month = apr,

day = "19",

doi = "10.3390/cancers14092057",

language = "English",

volume = "14",

journal = "Cancers",

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Ungefroren, H, Thürling, I, Färber, B, Kowalke, T, Fischer, T, De Assis, LVM, Braun, R, Castven, D, Oster, H, Konukiewitz, B, Wellner, UF, Lehnert, H & Marquardt, J-U 2022, 'The Quasimesenchymal Pancreatic Ductal Epithelial Cell Line PANC-1-A Useful Model to Study Clonal Heterogeneity and EMT Subtype Shifting', Cancers, vol. 14, no. 9, 2057. https://doi.org/10.3390/cancers14092057

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T1 - The Quasimesenchymal Pancreatic Ductal Epithelial Cell Line PANC-1-A Useful Model to Study Clonal Heterogeneity and EMT Subtype Shifting

AU - Ungefroren, Hendrik

AU - Thürling, Isabel

AU - Färber, Benedikt

AU - Kowalke, Tanja

AU - Fischer, Tanja

AU - De Assis, Leonardo Vinícius Monteiro

AU - Braun, Rüdiger

AU - Castven, Darko

AU - Oster, Henrik

AU - Konukiewitz, Björn

AU - Wellner, Ulrich Friedrich

AU - Lehnert, Hendrik

AU - Marquardt, Jens-Uwe

PY - 2022/4/19

Y1 - 2022/4/19

KW - EMT

KW - MET

KW - PANC‐1

KW - epithelial–mesenchymal plasticity

KW - intratumoral heterogeneity

KW - pancreatic ductal adenocarcinoma

KW - phenotype

KW - proinflammatory cytokines

KW - transdifferentiation

KW - transforming growth factor β

KW - transforming growth factor beta

KW - epithelial-mesenchymal plasticity

KW - PANC-1

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U2 - 10.3390/cancers14092057

DO - 10.3390/cancers14092057

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SN - 2072-6694

VL - 14

JO - Cancers

JF - Cancers

IS - 9

M1 - 2057

ER -

The Quasimesenchymal Pancreatic Ductal Epithelial Cell Line PANC-1-A Useful Model to Study Clonal Heterogeneity and EMT Subtype Shifting

Bibliographical note

Keywords

Fields of Science and Technology Classification 2012

Access to Document

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